The mean platelet volume (MPV) is sometimes ordered in conjunction with a platelet count. The MPV indicates the uniformity of size of the platelet population. It is used for the differential diagnosis of thrombocytopenia.
The relative size of platelets varies with platelet production . When the overall platelet count drops, functioning bone marrow produces younger and larger platelets to compensate for the decreased number of platelets. This process results in an increased mean platelet volume. Lack of bone marrow function results in the decreased production of platelets, a diminished platelet size, and a decreased mean platelet volume.
Adults: 7.4–10.4 µm3 or fL